Searchable abstracts of presentations at key conferences in endocrinology

ea0014p566 | (1) | ECE2007

Cerebrospinal fluid (CSF)/serum albumin ratio shows no alteration of the blood-brain barrier in patients with pituitary adenomas and high CSF levels of pituitary hormones

Gheorghiu Monica Livia , Purice Mariana , Rusu Catrinel , Galoiu Simona , Tanasescu Ruxandra , Niculescu Dan , Coculescu Mihai

Some patients with pituitary adenomas show high CSF levels and/or high CSF/serum ratio for peptidic pituitary hormones (PR), potentially due to a blood-brain barrier (BBB) damage. We evaluated albumin.CSF/serum ratio (AR) in patients with pituitary adenomas and elevated PR, as an accurate index for a BBB damage.Patients and methods: We evaluated 10 controls (21–79 years, 6M /4 F) before undergoing abdominal or peripheral surgery and 52 patients with...